Surgical aortic valve replacement in Australia, 2002-2015: temporal changes in clinical practice, patient profiles and outcomes.

This study describes the temporal changes in risk profiles and outcomes among patients with aortic stenosis (AS) undergoing surgical aortic valve replacement (SAVR) in Australia between 2002 and 2015.Using the Australian and New Zealand Society of Cardiac and Thoracic Surgeons database, we identified first-recorded SAVR for AS over 14 years.

Patients’ surgical risk profiles, procedures, 30-day and 12-month outcomes were summarized before and after the introduction of transcatheter aortic valve implantation in Australia, in 2008.

We applied multivariable regression models to investigate the changes over time on risk-adjusted 30-day mortality, re-hospitalization and 12-month mortality.We identify a total of 18 147 patients with AS who underwent SAVR; mostly men (64%) with a mean age of 72 years.

The proportion of major cardiac surgeries devoted to SAVR increased from 14% in 2002 to 20% in 2015. More SAVRs were performed electively (80% in 2002 versus 86% in 2015), and the recipients were at lower surgical risk (mean multi-risk score 3.9% in 2002 versus 3.0% in 2015).

4-ArmPEG-SAA,10K
33-A44015-10K	Biochempeg	EUR 174.00 EUR 420.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

4-ArmPEG-SAA,20K
33-A44015-20K	Biochempeg	EUR 174.00 EUR 420.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

4-ArmPEG-SAA,2K
33-A44015-2K	Biochempeg	EUR 198.00 EUR 494.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Bovine Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-b-48T	DL Develop	48T	EUR 547
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Serum Amyloid A (SAA) in samples from serum, plasma or other biological fluids.

Bovine Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-b-96T	DL Develop	96T	EUR 715
Description: A sandwich quantitative ELISA assay kit for detection of Bovine Serum Amyloid A (SAA) in samples from serum, plasma or other biological fluids.

Human Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-Hu-48T	DL Develop	48T	EUR 479
Description: A sandwich quantitative ELISA assay kit for detection of Human Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-Hu-96T	DL Develop	96T	EUR 621
Description: A sandwich quantitative ELISA assay kit for detection of Human Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-Mu-48T	DL Develop	48T	EUR 489
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-Mu-96T	DL Develop	96T	EUR 635
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-Rb-48T	DL Develop	48T	EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Serum Amyloid A (SAA) ELISA Kit
DLR-SAA-Rb-96T	DL Develop	96T	EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-b-48Tests	Reddot Biotech	48 Tests	EUR 580

Bovine Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-b-96Tests	Reddot Biotech	96 Tests	EUR 807

Human Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-Hu-48Tests	Reddot Biotech	48 Tests	EUR 500

Human Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-Hu-96Tests	Reddot Biotech	96 Tests	EUR 692

Mouse Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-Mu-48Tests	Reddot Biotech	48 Tests	EUR 511

Mouse Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-Mu-96Tests	Reddot Biotech	96 Tests	EUR 709

Rabbit Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-Rb-48Tests	Reddot Biotech	48 Tests	EUR 534

Rabbit Serum Amyloid A (SAA) ELISA Kit
RDR-SAA-Rb-96Tests	Reddot Biotech	96 Tests	EUR 742

Bovine Serum Amyloid A (SAA) ELISA Kit
RD-SAA-b-48Tests	Reddot Biotech	48 Tests	EUR 555

Bovine Serum Amyloid A (SAA) ELISA Kit
RD-SAA-b-96Tests	Reddot Biotech	96 Tests	EUR 771

Human Serum Amyloid A (SAA) ELISA Kit
RD-SAA-Hu-48Tests	Reddot Biotech	48 Tests	EUR 478

Human Serum Amyloid A (SAA) ELISA Kit
RD-SAA-Hu-96Tests	Reddot Biotech	96 Tests	EUR 662

Mouse Serum Amyloid A (SAA) ELISA Kit
RD-SAA-Mu-48Tests	Reddot Biotech	48 Tests	EUR 489

Mouse Serum Amyloid A (SAA) ELISA Kit
RD-SAA-Mu-96Tests	Reddot Biotech	96 Tests	EUR 677

Rabbit Serum Amyloid A (SAA) ELISA Kit
RD-SAA-Rb-48Tests	Reddot Biotech	48 Tests	EUR 511

Rabbit Serum Amyloid A (SAA) ELISA Kit
RD-SAA-Rb-96Tests	Reddot Biotech	96 Tests	EUR 709

TruStrip RDT Human Serum Amyloid A (SAA) Rapid Test cards, 10 tests/pack
SAA-RDT-10	Alpha Diagnostics	1 pack	EUR 171

TruStrip RDT Human Serum Amyloid A (SAA) Rapid Test cards, 25 tests/pack
SAA-RDT-25	Alpha Diagnostics	1 pack	EUR 293

SAA-PEG-SAA
abx085047-10kDa1g	Abbexa	10 kDa; 1 g	EUR 453

SAA-PEG-SAA
abx085047-1kDa1g	Abbexa	1 kDa; 1 g	EUR 453

SAA-PEG-SAA
abx085047-20kDa1g	Abbexa	20 kDa; 1 g	EUR 453

SAA-PEG-SAA
abx085047-2kDa1g	Abbexa	2 kDa; 1 g	EUR 453

SAA-PEG-SAA,10K
33-HO015015-10K	Biochempeg	EUR 259.00 EUR 677.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,1K
33-HO015015-1K	Biochempeg	EUR 259.00 EUR 677.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,20K
33-HO015015-20K	Biochempeg	EUR 259.00 EUR 677.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,2K
33-HO015015-2K	Biochempeg	EUR 259.00 EUR 677.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,3.4K
33-HO015015-3.4K	Biochempeg	EUR 259.00 EUR 677.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,5K
33-HO015015-5K	Biochempeg	EUR 259.00 EUR 677.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA
E64C01201	EnoGene	20ug	EUR 382

IL-4 Interleukin 4 Human Recombinant Protein, Yeast
PROTP05112-4	BosterBio	Regular: 10ug	EUR 317
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Individual Reaction Mix 4
G065-4	ABM	200 reactions	EUR 167

SAA Protein
abx060299-100ug	Abbexa	100 ug	EUR 829

mPEG-SAA
abx085023-10kDa1g	Abbexa	10 kDa; 1 g	EUR 370

mPEG-SAA
abx085023-1kDa1g	Abbexa	1 kDa; 1 g	EUR 356

mPEG-SAA
abx085023-20kDa1g	Abbexa	20 kDa; 1 g	EUR 370

mPEG-SAA
abx085023-2kDa1g	Abbexa	2 kDa; 1 g	EUR 356

mPEG-SAA
abx085023-5kDa1g	Abbexa	5 kDa; 1 g	EUR 356

Bovine(SAA)
QY-E60061	Qayee Biotechnology	96T	EUR 426

SAA antibody
10-7959	Fitzgerald	500 ug	EUR 349
Description: Mouse monoclonal SAA antibody

SAA antibody
10-7960	Fitzgerald	500 ug	EUR 349
Description: Mouse monoclonal SAA antibody

SAA antibody
10R-10351	Fitzgerald	100 ug	EUR 435
Description: Mouse monoclonal SAA antibody

SAA antibody
20-1715	Fitzgerald	1 ml	EUR 138
Description: Goat polyclonal SAA antibody

Feline IL-4 Recombinant Protein
R00230-4	BosterBio	5ug/vial	EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

pLenti-CLDN1 shRNA-4 Plasmid
PVTBAV04867-4	Lifescience Market	2 ug	EUR 356

Recombinant Human PF-4 (CXCL4) Protein
PROTP02776-4	BosterBio	20ug	EUR 317
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Mouse FibrOut 4, for brain, neural
4-20507	CHI Scientific	1 ml	Ask for price

Mouse FibrOut 4, for brain, neural
4-20508	CHI Scientific	5 x 1 ml	Ask for price

Rat FibrOut 4, for brain, neural
4-20533	CHI Scientific	1 ml	Ask for price

Rat FibrOut 4, for brain, neural
4-20534	CHI Scientific	5 x 1 ml	Ask for price

Human FibrOut 4, for brain, neural
4-21552	CHI Scientific	1 ml	Ask for price

Human FibrOut 4, for brain, neural
4-21553	CHI Scientific	5 x 1 ml	Ask for price

DIGITAL SHAKER FOR 4 MICROPLATES, 120V
6780-4	CORNING	1/pk	EUR 798
Description: Lab Equipment; Shakers & Mixers

Recombinant Human 4-1BB Receptor Protein
PROTQ07011-4	BosterBio	20ug	EUR 317
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Bone Dissociation System 4 (Osteoblasts), Adult Mouse
4-20214	CHI Scientific	ea	Ask for price

Liver Dissociation System 4 (Hepatocytes, rat), Rat
4-20304	CHI Scientific	ea	Ask for price

Pituitary Dissociation System 4 (Pituitary), Adult mouse
4-20404	CHI Scientific	ea	Ask for price

Thymus Dissociation System 4 (Epithelial), Adult rat
4-20444	CHI Scientific	ea	Ask for price

mPEG-SAA,10K
33-MF001015-10K	Biochempeg	EUR 211.00 EUR 531.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,1K
33-MF001015-1K	Biochempeg	EUR 198.00 EUR 494.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,20K
33-MF001015-20K	Biochempeg	EUR 211.00 EUR 531.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,2K
33-MF001015-2K	Biochempeg	EUR 198.00 EUR 494.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,30K
33-MF001015-30K	Biochempeg	EUR 211.00 EUR 531.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,4K
33-MF001015-4K	Biochempeg	EUR 198.00 EUR 494.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,5K
33-MF001015-5K	Biochempeg	EUR 198.00 EUR 494.00	1g 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Recombinant Human SAA
P0209	FN Test	100ug	EUR 522.36
Description: Recombinant Human protein for SAA

Apo SAA antibody
20R-1792	Fitzgerald	100 ug	EUR 673
Description: Rabbit polyclonal Apo SAA antibody

Cartilage Dissociation System 4 (Chondrocytes), Mouse and Rat
4-20234	CHI Scientific	ea	Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse
4-20324	CHI Scientific	ea	Ask for price

Pancreas Dissociation System 4 (Islets), Mouse and Rat
4-20374	CHI Scientific	ea	Ask for price

Skin Dissociation System 4 (Keratinocytes), Mouse and Rat
4-20434	CHI Scientific	ea	Ask for price

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-EU PLUG
6781-4	CORNING	1/pk	EUR 798
Description: Lab Equipment; Shakers & Mixers

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-UK PLUG
6782-4	CORNING	1/pk	EUR 798
Description: Lab Equipment; Shakers & Mixers

Adipose/Fat Dissociation System 4 (Predipocytes), Mouse and Rat
4-20194	CHI Scientific	ea	Ask for price

Brain Dissociation System 4 (Endothelial, Microvessels), Mouse and Rat
4-20224	CHI Scientific	ea	Ask for price

Endothelial Dissociation System 4 (Endothelial,Cerebral), Mouse and Rat
4-20244	CHI Scientific	ea	Ask for price

Heart Dissociation System 4 (Myocytes,Ventricles), Mouse and Rat
4-20274	CHI Scientific	ea	Ask for price

Muscle Dissociation System 4 (Smooth muscle), Mouse and Rat
4-20334	CHI Scientific	ea	Ask for price

Parotid Dissociation System 4 (Parotid acinar), Mouse and Rat
4-20394	CHI Scientific	ea	Ask for price

Epithelial Dissociation System 4 (Epithelial,Submandibular salivary), Mouse and Rat
4-20254	CHI Scientific	ea	Ask for price

Heart Dissociation System 4 (Retinal pigment epithelial), Mouse and Rat
4-20294	CHI Scientific	ea	Ask for price

Lung Dissociation System 4 (Alveolar type II), Mouse and Rat
4-20314	CHI Scientific	ea	Ask for price

Reproductive Tissue Dissociation System 4 (Epithelial, vagina), Mouse and Rat
4-20414	CHI Scientific	ea	Ask for price

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 4 vials)
M1040-4	Biovision		EUR 909

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 4 vials)
M1041-4	Biovision		EUR 1137

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 4 vials)
M1042-4	Biovision		EUR 909

The use of bioprosthetic aortic valves increased over time (67% in 2002 to 88% in 2015). We found no significant changes in 30-day mortality, a significant decrease in 30-day readmission and minor fluctuations in 12-month mortality over the study period.SAVR comprises an increasingly larger proportion of all adult cardiac surgeries in Australia. There has been a greater use of bioprosthetic aortic valves, a fall in 30-day readmission but no significant changes in mortality.